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| GAIT STUDY |
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Click here for the complete GAIT abstract |
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Click here for a glossary of helpful terms |
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Study Overview |
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This study, sponsored by the National Institutes of Health, evaluated the safety and ability of 1500 mg Glucosamine (G) and 1200 mg chondroitin sulfate (CS) to reduce joint pain alone and when taken together, compared with celecoxib (CE), the standard joint pain treatment. |
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Results |
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The combination of glucosamine and chondroitin sulfate (G + CS) was shown to be more effective than a common pain reliever celecoxib (CE), in people with severe pain due to OA. |
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The authors theorized that they did not see a result in patients with mild pain due to a floor effect in that the change in pain was too minor to be detected. |
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| GUIDE STUDY |
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Click here for the complete GUIDE abstract |
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Click here for a glossary of helpful terms |
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Study Overview |
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GUIDE is a European study that measured the effectiveness of 1500 mg glucosamine
to treat knee OA compared with acetaminophen - the preferred treatment in OA practice guidelines.
The study population consisted of more than 300 patients who took either 1500 mg glucosamine or 1000 mg acetaminophen or placebo for six months. |
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Results |
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Glucosamine sulfate was significantly more effective in its ability to ease joint pain compared with placebo. |
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Acetaminophen - the conventional treatment for joint pain - was no better than placebo. |
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There was no difference among groups in safety. |
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